{"id":142800,"date":"2020-03-20T16:40:48","date_gmt":"2020-03-20T16:40:48","guid":{"rendered":"https:\/\/www.bnreport.com\/trump-focuses-attention-on-possible-coronavirus-treatments\/"},"modified":"2020-03-20T16:40:48","modified_gmt":"2020-03-20T16:40:48","slug":"trump-focuses-attention-on-possible-coronavirus-treatments","status":"publish","type":"post","link":"https:\/\/www.bnreport.com\/en\/trump-focuses-attention-on-possible-coronavirus-treatments\/","title":{"rendered":"Trump Focuses Attention on Possible Coronavirus Treatments"},"content":{"rendered":"<p>President Donald Trump focused attention on possible treatments for the new coronavirus on Thursday, citing potential use of a drug long used to treat malaria and some other approaches still in testing.<\/p>\n<p>At a White House news conference, Trump and Food and Drug Administration Commissioner Dr. Stephen Hahn cited the malaria drug chloroquine, along with remdesivir, an experimental antiviral from Gilead Sciences, and possibly using plasma from survivors of COVID-19, the disease the new virus causes.<\/p>\n<p>Those treatments are among several being tested that might ease symptoms but do not stop the virus from spreading.<\/p>\n<p>Also on Thursday, Swiss drugmaker Roche said it was working with the U.S. government to start a study of Actemra, a drug used now for rheumatoid arthritis and some other conditions, against the coronavirus.<\/p>\n<p>\u201cWere looking at drugs that are already approved for other indications\u201d as a potential bridge or stopgap, Hahn said, while also doing rigorous studies to see if the drugs truly make a difference versus usual care, and if they are safe when used for a new purpose.<\/p>\n<p>\u201cWe want to make sure this is done well and right,\u201d he said.<\/p>\n<p>No drug is specifically approved now for treating COVID-19.<\/p>\n<p>Chloroquine and a similar drug \u2014 hydroxychloroquine, sold as Plaquenil by French drugmaker Sanofi and in generic form \u2014 are available now and can be used off-label in the United States. They may interfere with the coronavirus being able to enter cells, and some scientists have reported possible encouraging signs in test-tube and other small studies.<\/p>\n<p>German drugmaker Bayer has said it would donate 3 million tablets of its chloroquine drug, Resochin, for use against coronavirus. That drug was never approved in the U.S., so Bayer is working with federal agencies to get an emergency-use authorization.<\/p>\n<p>Chloroquine and remdesivir are among the drugs the World Health Organization said would be tried in a five-part international study announced Wednesday.<\/p>\n<p>Already approved drugs are tempting for doctors to use off label, but formal studies are needed to see if they truly work for a new purpose or disease, said Dr. Ross McKinney Jr., chief scientific officer for the Association of American Medical Colleges, which represents about 400 major teaching hospitals across the country.<\/p>\n<p>Chloroquine may look promising in a test tube, but \u201cIm skeptical it will be effective\u201d in patients, he said Thursday in a call with reporters.<\/p>\n<p>Remdesivir interferes with virus reproduction and has shown some promise in lab and animal studies against other coronaviruses that cause similar diseases, MERS and SARS.<\/p>\n<p>Its being tested in at least five separate experiments, and Gilead also has given it to several hundred severely ill patients in the U.S, Europe and Japan under \u201ccompassionate use\u201d provisions. That includes three of the first dozen COVID-19 patients in the United States.<\/p>\n<p>They recovered, but its impossible to know whether they would have anyway without the drug.<\/p>\n<p>On a podcast Wednesday with a medical journal editor, the National Institutes of Healths Dr. Anthony Fauci said China had enrolled several hundred people in its two remdesivir studies but is having trouble recruiting more because many patients just want the drug and are unwilling to take a chance on being randomly assigned to a comparison group that just gets usual care.<\/p>\n<p>It would be great if an independent monitoring board could look at results so far and see if there are signs of safety or effectiveness, Fauci said.<\/p>\n<p>\u201cWe desperately need the data\u201d on this and other drugs being tested in rigorous scientific studies, Fauci said. \u201cWeve got to be able to determine if they work and if theyre safe.\u201d<\/p>\n<p>Apart from the studies in China, Faucis agency is running a study of remdesivir that aims to recruit 400 patients in the U.S. and elsewhere. That study is \u201cadaptive,\u201d meaning it will allow scientists to add other drugs under the same testing umbrella as time goes on. Gilead also has said it will do two studies testing remdesivir treatment for five or 10 days in about 1,000 hospitalized patients primarily in Asia.<\/p>\n<p>Remdesivir \u201cdoes look like it could be promising,\u201d said Dr. Daniel Kuritzkes, chief of infectious diseases at Brigham and Womens Hospital in Boston. In animal tests, it was \u201cquite effective at preventing infection\u201d and reducing severity of illness and damage to the lungs when given early enough in the course of illness, he said.<\/p>\n<p>\u201cIt interferes with the enzyme that reproduces the genetic material of the virus\u201d and acts at an earlier step than protease inhibitors such<a href=\"https:\/\/www.theepochtimes.com\/trump-focuses-attention-on-possible-coronavirus-treatments_3279339.html\" rel=\"noreferrer noopener\" target=\"_blank\">Read More \u2013 Source<\/a><br \/>\n[contf]<br \/>\n[contfnew]<br \/>\n        <img decoding=\"async\" src=\"https:\/\/www.ninebyninedesign.com\/wp-content\/uploads\/2017\/08\/download.png\" \/><\/p>\n<h5><a href=\"https:\/\/www.theepochtimes.com\/\" rel=\"noreferrer noopener\" target=\"_blank\">The Epoch Times<\/a><\/h5>\n<p>[contfnewc]<br \/>\n[contfnewc]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>President Donald Trump focused attention on possible treatments for the new coronavirus on Thursday,..<\/p>\n","protected":false},"author":1,"featured_media":142801,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[],"class_list":["post-142800","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-politics"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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